At a time when the boundaries of medical science and technology are increasingly overlapping, one private company has taken the world to a completely new level, and could be the start of a new millennia of neural interfacing. Precision Neuroscience recently announced that it had implanted 4,096 electrodes onto a living human brain, doubling the previous milestone, while developing the furthest along the innovation curve with neurotechnology and neuroscience.
The feat is more than a number, because high electrode density ensures that neuroscientists can map neuronal activity where it occurs – with unparalleled resolution. In the longer term, scientists hope to use this permanent electrode grid to improve the decoding of thoughts into intended actions, a step that offers tremendous promise for the millions of people who have suffered strokes, spinal cord injuries or other ailments that impede speech and movement.
Unlike its competitors, Precision Neuroscience has emphasised minimal invasiveness, scalability and safety. Following in DARPA’s footsteps but diverging from its younger compatriot in the BCI arms race Neuralink, its designs are less invasive to the human brain but still aim for the same grandiose goal of restoring lost function.
Precision Neuroscience was conceived in an unlikely fork in the road. Co-founded by Ben Rapoport, a former co-founder of Neuralink, Precision was born out of concerns for the safety of more invasive BCI implants. After Rapoport left Neuralink and founded the company with colleagues, he did so with the goal of developing neural interfaces that could collect rich data from the brain without damaging it in the process.
Rapoport saw little point in testing neural interfaces that would damage brains. As someone who had lost his 16-year-old son to a hernia operation gone wrong, he wanted neural interfaces to be moved from the lab into medical reality, and he wanted them to be safe first, data-gathering second. That’s the philosophy behind Precision: it’s all about reducing the risks of brain damage, whatever the gadget’s data-extraction potential might be.
A flagship product being developed by the company, Precision, showcases its cutting-edge approach. Unlike previous BCI devices that require drilling holes in the skull and extracting parts of the brain before inserting electrodes directly into the tissue, Precision’s technology sits on the brain with ultra-thin films covered in micro-electrodes. This minimally invasive approach not only greatly increases the safety for the patient but also allows the collection of incredibly fine-grained maps of the brain.
But that’s not the primary point; the power of precision’s device isn’t in its sheer electrode number; instead, the array can be ‘scaled up to add as many electrode-containing films as needed for clinical requirements’, according to the researchers. Its modular design means that it’s easily adaptable – a must in all precision medicine: one measurement isn’t going to serve the needs of every individual patient.
The nerve-signal extravaganza Precision performed to set the record might be the harbinger of what comes next. Detailed neuronal circuit activity sampled within a large swath of the brain – a recent product of the record-implantation event – provides a tantalising preview of what neurotechnology may afford soon.
With a commercial launch planned for 2025, Precision Neuro is far from just a first, but rather a forebear of a new and dazzling world of human brain-interaction. As the company moves forward, the implications for medical science, patient care and our fundamental understanding of the human mind are likely to unfold in a myriad and profound ways.
Like any great story, that of Precision Neuroscience is a tale about progress, with ‘moving on’ a central theme: moving on from invasive methods, moving on from experimental dangers and moving into the future of scalable safety; ultimately, moving neurotechnology from open brain to closed loop. It’s a tale that embodies the symphony of innovation in bCIs, featuring two particularly beautiful ‘moves’; from move to mind the ‘mover’ is patient well-being, and from move to micro the ‘mover’ is electrode innovation.
Standing at the start of a world of new discoveries and possibilities, Precision Neuroscience’s monumental move isn’t just a record-breaking moment: it’s the next stop on a trajectory that extends into a future where the latent potential of the human brain could be revealed in ways we are only now beginning to imagine.
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